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The main ingredient of this product is lurasidone hydrochloride
This product is a white or off white circular film coating.
Schizophrenia.
40mg (calculated as C28H36N4O2S · HCl)
The initial dose for adults is usually 40 mg per dose, once daily, and titration is not required for the initial dose. According to the symptoms, it can be increased to 80mg once a day. This product should be taken with food (at least 350 calories).
The recommended initial dose for patients with moderate (creatinine clearance rate: 30-<50 mL/min) and severe (creatinine clearance rate:<30 mL/min) renal impairment is 20mg/day. The maximum dose is 80 mg per dose, once daily.
The recommended initial dose for patients with moderate (Child Pugh score=7-9) and severe (Child Pugh score=10-15) liver injury is 20mg/day. The maximum dose for patients with moderate liver injury is 80 mg once daily, while for patients with severe liver injury it is 40 mg once daily.
When used in combination with CYP3A4 intermediate acting inhibitors (such as diltiazem), the initial dose should be halved. The maximum dose is 80 mg per dose, once daily.
Due to the fact that grapefruit and grapefruit juice may inhibit CYP3A4 and alter the concentration of liraglutide, patients taking liraglutide should avoid consuming grapefruit and grapefruit juice.
When used in combination with CYP3A4 inducers, it may be necessary to increase the dose of liraglutide after a period of treatment (7 days or longer) with CYP3A4 inducers.
Lurasidone should not be used in combination with CYP3A4 potent inhibitors (such as ketoconazole, clarithromycin, ritonavir, voriconazole, mibelapidil, etc.) and potent inducers (such as rifampicin, avamab, St. John's wort, phenytoin, carbamazepine, etc.)
Sealed storage at no more than 30 ℃. Please keep this product out of reach of children.
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